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| Director: Prof. Andreas A. Linninger |
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| BioE 494 |
Fall 2005 |
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Metabolic Reaction Engineering (BioE 494) |
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This course is designed to develop a fundamental understanding about biochemical reactions and the directed improvement of cellular properties in order to achieve certain industrial and medical goals. This is an interdisciplinary field at the interface of chemical engineering, biochemistry, molecular and cell biology, and the computational sciences. The aim of this course is to provide an introduction to the principles and methodology of metabolic engineering. The course will cover experimental and mathematical techniques for the quantitative description, modeling, control and design of metabolic pathways. The course will consist of lecture and discussion section as well as student projects. In the students’ projects, analytical software tools and design environments, e.g. MATLAB, PLAS, etc. will be used. Case studies will illustrate the applications of system theory in Metabloic Reaction Engineering..
Textbook/Notes:
Computational
Analysis of Biochemical Systems: A practical guide for Biochemists and
Molecular Biologists.
E. O. Voit, Cambridge University Press, 2000
Metabolic Engineering: Principles and Methodologies. G. Stephanopoulos,
A. Aristidou and J. Nielsen, Academic Press, 1998.
Additional material will be provided in class in the form of research papers and lecture notes.
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