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| Director: Prof. Andreas A. Linninger |
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Selected Publications and Presentations | |||||||||||||||||||||||||||||||||||||||||||||
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| 2007 | ||||||||||||||||||||||||||||||||||||||||||||||
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A. Malcolm, L. Zhang, A.A. Linninger, "Optimal regulation for sustainable drug manufacturing", International J. of Environment and Pollution, 29 (1-3), pp 144-164, 2007. [...]
A.A. Linninger, M.R. Somayaji, M. Mekarski, L. Zhang, "Prediction of convection-enhanced drug delivery to the human brain", Journal of Theoretical Biology, 250, pp 125-138,2008. [...]
A. Malcolm, J. Polan, L. Zhang, B. Oguannaike, A.A. Linninger, "Integrating systems design and control using dynamic flexibility analysis", AIChE Journal, 53 (8), pp 2048-2061, 2007. [...]
L. Zhang, K. Kulkarni, M.R. Somayaji, M. Xenos, A.A. Linninger, "Discovery of transport and reaction properties in distributed systems", AIChE Journal, 53 (2), pp 381-396, 2007. [...]
M.R. Somayaj, M. Xenos, L. Zhang, M. Megarski, A.A. Linninger, "Systematic design of drug delivery therapies", Comp. Chem. Eng., 32, pp 89-98, 2008 [...]
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| 2006 | ||||||||||||||||||||||||||||||||||||||||||||||
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A.A. Linninger, M. Xenos, D. Zhu, M.R. Somayaji, R. Penn, "Cerebrospinal fluid flow in the normal and hydrocephalic human brain", IEEE Transactions on Biomedical Engineering, 54 (2), pp 291-302, 2006. [...]
L. Zhang, C. Xue, A. Malcolm, K. Kulkarni, A.A. Linninger, "Distributed system design under uncertainty", Ind. Eng. Chem. Res., 45 (25), pp 8252-8360, 2006. [...]
A. Malcolm, L. Zhang, A.A. Linninger, " Design of environmental regulatory policies for sustainable emission reduction", AIChE Journal, 52 (8), pp 2792-2804, 2006. [...]
D. Zhu, M. Xenos, A.A. Linninger, R. Penn, " Dynamics of lateral ventricle and cerebrospinal fluid in normal and hydrocephalic brains ", Journal of magnetic resonance imaging, 24, pp 756-770, 2006. [...]
K. Kulkarni, L. Zhang, A.A. Linninger, "Model and parameter uncertainty in distributed systems", Ind. Eng. Chem. Res.,45 (23); 7832-7840, 2006. [...]
L. Zhang, A.A. Linninger, "Towards computer-aided separation synthesis", AIChE Journal, 52 (4), pp 1392-1409, 2006. [...]
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2005 | ||||||||||||||||||||||||||||||||||||||||||||||
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A.A. Linninger, C. Tsakiris, Zhu, M. Xenos, P. Roycewicz, Z. Danziger, R.Penn,"Pulsatile cerebrospinal fluid dynamics in the human brain", IEEE Transactions on Biomedical Engineering, 52(4), pp 557-565, 2005. [...] W. Tang, L. Zhang, A.A. Linninger, R.Tranter, K. Brezinsky, "Solving kinetic inversion problems via a physically bounded Gauss-Newton (PGN) method", Ind. Eng. Chem. Res., 44(10), pp 3626-3637, 2005. [...] R.D. Penn, M.C, Lee, A.A. Linninger, K. Miesel, S.N. Lu, L. Stylos, "Pressure gradients in the brain: an experimental model of hydrocephalus", J. Neurosurgery, pp 1069-1075, 2005. [...] | ||||||||||||||||||||||||||||||||||||||||||||||
| 2004 | ||||||||||||||||||||||||||||||||||||||||||||||
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S. Chowdhry, H. Krendl, A.A. Linninger, "Symbolic numeric index analysis algorithm for differential algebraic equations", Ind. Eng. Chem. Res., 43, pp 3886-3894, 2004. [...] L. Zhang, A.A. Linninger, "Temperature collocation algorithm for fast and robust distillation design", Ind. Eng. Chem. Res., 43, pp 3163-3182, 2004 . [...] A. Chakraborty, A. Malcolm , A.A. Linninger, "Pharmaceuticals product-only design", Proceedings of FOCAPD-2004 Conference Proceedings, pp 347-351, 2004. [...] A. Chakraborty , A. Malcolm , R.D. Colberg, , A.A. Linninger , "Optimal waste reduction and investment planning under uncertainty", Computers and Chemical Engineering, 28(7), pp 1145-1156, 2004. [...] A. Chakraborty , K. Purkarthofer, A.A. Linninger, "Conceptual design of metallurgical processes based on thermodynamic and economic insights", Chemical Engineering Progress, 43, pp 625- 640, 2004. [...] | ||||||||||||||||||||||||||||||||||||||||||||||
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2003 | ||||||||||||||||||||||||||||||||||||||||||||||
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A. Chakraborty, A.A. Linninger, "Plant-wide waste management 2. Decision making under uncertainty", Ind. Eng. Chem. Res., 42, pp 357- 369, 2003. [...] A. Chakraborty, A.A. Linninger, "Plant-wide waste management. 3. Long term operation and investment planning under uncertainty", Ind. Eng. Chem. Res., 42, pp 4772 - 4788, 2003. [...] A. Chakraborty, A.A. Linninger,R.D. Colberg, "Optimal waste reduction and investment planning under uncertainty", Proceedings of the FOCAPO-2003 Conference, 2003. [...] | ||||||||||||||||||||||||||||||||||||||||||||||
| 2002 | ||||||||||||||||||||||||||||||||||||||||||||||
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A. Chakraborty, A.A. Linninger, "Plant-Wide waste management. 1. Synthesis and multi-objective design", Ind. Eng. Chem. Res., 41 (18), pp 4591 - 4604, 2002. [...] A.A. Linninger , "Metallurgical process design A tribute to Douglass conceptual design approach", Ind Eng. Chem. Res., 41(16), pp. 3797- 3805, 2002. [...] | ||||||||||||||||||||||||||||||||||||||||||||||
| 2001 | ||||||||||||||||||||||||||||||||||||||||||||||
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A.A. Linninger, A. Chakraborty, G. Stephanopoulos, "Screening of recovery and treatment options for waste minimization". In "Process design tools for the environment", S. K. Sikdar, M. El-Halwagi (Eds), Taylor and Francis, London, 2001. [...] A.A. Linninger, "Modeling and simulation of metallurgical processes", BMH, Springer Verlag, 146 (9), pp 369-372, 2001. [...] A.A. Linninger,A. Chakraborty, "Pharmaceutical waste management under uncertainty", Comp. Chem. Eng., 25, pp 675-681, 2001. [...] V. Bahl, A. A. Linninger, "Modeling of event-driven continuous-discrete processes", Lecture notes in computer science 2034, Springer Verlag, pp 387- 402, ISBN 3-540-41866-0, 2001. [...] S. Chowdhry, A. A. Linninger, "Automatic structure analysis of large scale differential algebraic systems", Proc. IEEE instrumentation and measurement technology conference, Budapest, May 21 - 23, 2001. in press. DownLoad pdf A.A. Linninger, "Recent advances in process systems engineering", Proc. IEEE Instrumentation and Measurement Technology Conference, Budapest, May 21- 23, 2001. in press. [...] A. Chakraborty, A. A. Linninger, "Plant-wide waste management. 1. synthesis and multi-objective design", Industrial and Engineering Chemistry Research, September 2001. [...] A.A. Linninger, "Towards computer-aided model generation", Keynote Lecture, Japan Society for the Promotion of Science (JSPS) International Workshop on Safety-Assured Operation and Concurrent Engineering, Sponsored by Japan Society for the Promotion of Science, Yokohama, Japan,December 3-5, 2000 . [...] | ||||||||||||||||||||||||||||||||||||||||||||||
| 2000 | ||||||||||||||||||||||||||||||||||||||||||||||
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A.A. Linninger, "Metamodeling a novel approach for phenomena-oriented model generation", AICHE Symposium Series, 96 (323), pp 462 - 465, 2000. [...] A.A. Linninger, A. Chakraborty, R. Colberg, "Planning of waste reduction strategies under uncertainty", Comp. Chem. Eng., 24, 1043 - 1048, 2000. [...] A.A Linninger, S. Chowdhry, V. Bahl, H. Krendl, H. Pinger, "A systems approach to mathematical modeling of industrial processes", Comp. Chem. Eng., 24, 591 - 598, 2000. [...] V. Bahl, A. A. Linninger, "Hybrid simulation of continuous discrete systems", Proc. ESCAPE-10, Florence, pp 163 168, S. Pierucci (Ed.),Elsevier, Amsterdam, 2000. [...] A.A. Linninger, A. Chakraborty, "Decision-making for batch manufacturing sites under uncertainty", Proc. ESCAPE-10, Florence, pp 901 906, S. Pierucci (Ed.), Elsevier, 2000. [...] S. Chowdhry, A.A. Linninger, "Model simplification for dynamic systems", Proceeding in the 19th IASTED International Conference on Modeling Identification and Control, Innsbruck, Austria, Feb. 14 - 17, pp.452 456, 2000. V. Bahl, S. Chowdhry,A.A. Linninger, "A high level language for hybrid systems", Proceeding in the 19th IASTED International Conference on Modeling Identification and Control, Innsbruck, Austria, Feb. 14 - 17, pp. 608 - 614. 2000. A.A. Linninger, A. Chakraborty, "Design and analysis of optimal waste treatment policies", AICHE Symposium Series, 96 (323), pp 355 - 359, 2000. [...] G. Stephanopoulos, S. Ali, A.A. Linninger, E. Salomone, "Batch process development: challenging traditional approaches", AICHE Symposium Series, 96 (323), pp 46 - 57, 2000. | 1999 | |||||||||||||||||||||||||||||||||||||||||||||
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A.A. Linninger, H. Krendl, "TechTool - Computer-aided generation of process models (Part 1 - A Generic Mathematical Language)", Comp. Chem. Eng., 23, pp 703-706, 1999. [...] A.A. Linninger, A. Chakraborty, "Plant-wide optimal waste management", Comp. Chem. Eng., 23, pp 67-70, 1999. [...] A.A. Linninger ,A. Chakraborty, "Synthesis and optimization of waste treatment flowsheets", Comp. Chem. Eng., 23, pp 1415 1425, 1999. [...] A.A. Linninger, V. Bahl, "Integrated chemical engineering & industrial outreach - A new approach to design and chemical engineering practice", Proc. International conference on engineering education, Prague, Czech Republic, August, 1999. A. Chakraborty,A. A. Linninger, "Multi-objective Ddsign of batch operating procedures", Paper 216p, AIChE Annual Meeting, Oct. 31-Nov. 5, Dallas, TX, 1999. A. Chakraborty, A. A. Linninger, "Design of waste treatment policies under uncertainty", Paper 236b, AIChE Annual Meeting, Oct. 31-Nov. 5, Dallas, TX, 1999. A. Chakraborty, A.A. Linninger, "Systematic assessment of treatment policies for liquid wastes from pharmaceutical plants: a case study", Paper 24c, AICHE Spring National Meeting, March 14-18, 1999, Houston, Texas. A. Chakraborty, A.A. Linninger, "Synthesis of treatment flowsheets for pharmaceutical wastes", Paper 98c, AICHE Spring National Meeting, March 14-18, 1999, Houston, Texas. A.A. Linninger, V. Bahl, S. Chowhdry, H. Krendl, "TechTool - A process model generation environment", Proceeding in the 18th IASTED International Conference on Modeling Identification and Control 99, Innsbruck, Austria, Feb. 15 18, pp 370 - 373, 1999. G. Stephanopoulos, S. Ali, A.A. Linninger, E. Salomone, "Batch process development: from reactions to manufacturing systems", Comp. Chem. Eng., 23, pp 975-984, 1999. |
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| 1997-98 | ||||||||||||||||||||||||||||||||||||||||||||||
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S.Ali, A.A. Linninger, G. Stephanopoulos, " Synthesis of batch processing schemes as synthesis of operating procedures: a means-ends analysis and non-monotonic planning approach", paper 216c, AICHE Annual Meeting, Nov 15 - 20, Miami, Fl, 1998. A.A. Linninger, G. Stephanopoulos ," A natural language approach for the design of batch operating procedures", Informatica, Special issue on natural language processing and multi-agent systems, 22( 4), ISSN 0250-5596, 1998. A.A. Linninger, E. Salomone, S. Ali, E. Stephanopoulos, G. Stephanopoulos, "Pollution prevention for production systems of energetic materials", Waste Management Journal, 17, No 2/3, pp 165 173, 1998. A.A. Linninger, "Computer-aided model generation", Workshop with Voest Alpine industries, Linz, Austria, Aug. 10 14, 1998. A.A. Linninger,Computer-aided evolutionary process development in adaptation and evolution in embedded information systems, H. Franke, B. Kleinjohann, J. Sztipanovics (Eds), Dagstuhl Seminar Report, 226, ISSN 0940-1121, 1998. A. Linninger, "A Phenonena-driven process model generation environment", Conference for model integrated computing, Vanderbilt University, Nashville, TN, Aug 6 7, 1998. A.A. Linninger, " A corporate-wide initiative for integrated computer-aided process engineering", FOCAPO conference, Snowbird, Utah, July 5 10, 1998. A.A.Linninger, G. Stephanopoulos, "Cybernetics and systems" Proc. Of fourth European meeting on cybernetics and systems research, R. Trappl (Ed), Vol1, Vienna, Austria, 1998. C. Richardson, S. Sopher, R. Petak, A.A. Linninger,"Conceptual process design using symbolic and numerical computing techniques", MapleTech, Special Issue on Maple in Industry, ISSN 1061-5733, Vol 5, No 2/3, p. 3 14, 1998. A.A. Linninger, H. Krendl, H. Pinger, "An initiative for integrated computer-aided process engineering", AICHE Symposium Series, 94 (320), pp 494 - 500, 1998. |
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| 1995-96 | ||||||||||||||||||||||||||||||||||||||||||||||
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A.A. Linninger, S. A. Ali, G. Stephanopoulos, "Knowledge-based validation and waste management of batch pharmaceutical process designs", Comp. Chem. Eng., 20, pp 1431 - 1436, 1996. A.A. Linninger, M. Hofer, H. Krendl, H. Druckenthaner, H. P. Jörgl, "M-PROJECT - organizing problem representation and modeling of steady state and dynamic processes", Comp. Chem. Eng., 20, pp 425 - 430, 1996. A. A. Linninger, E. Stephanopoulos, S. A. Ali, E. Salomone, J. Aumond, G. Stephanopoulos. "BatchDesign-Kit - a comprehensive computer-aided design framework for batch process development with ecological considerations", Paper 146h, AICHE Annual Meeting, Chicago, IL, Nov, 1996. A. A. Linninger, E. Salomone, S. A. Ali, E. Stephanopoulos and G. Stephanopoulos. "Pollution prevention for production systems of energetic materials", Conference for life-cycles of energetic materials, Williamsburg, VI, Oct. 1996. A. A. Linninger, and G. Stephanopoulos, "Computer-aided waste management of pharmaceutical wastes", Paper 23a , AIChE Meeting, New Orleans, LA, 1996. A. A. Linninger, "Automatic flowsheet generation for waste treatment", Lecture at the University of Massachusetts, Amherst , 1996. A.A. Linninger, G. Stephanopoulos, "Life-cycle design (LCD) - reengineering the process design procedure" , Proc. 88th Annual Meeting Air&Waste Management Association, Paper 95-TA40A.02, San Antonio, TX, 1995. A.A. Linninger, M. Hofer, A. A. Patuzzi, "DynEAF - A dynamic modeling tool for integrated electric steelmaking", Iron and Steel Engineer, 72, 43-53, 1995. A.A. Linninger, S. A. Ali, E. Stephanopoulos, C. Han, G. Stephanopoulos, "Generation and assessment of batch processes with ecological considerations", Comp. Chem. Eng., 19, pp 7-13, 1995. A.A. Linninger, A. A. Patuzzi, "Modern technology and information management at the example of electric arc furnace design", Stahl und Eisen, 115, pp 93-101, 1995. A.A Linninger, G. Stephanopoulos, "Modern waste management using a technology assessment expert system", Paper 26a, AIChE Meeting, Boston, 1995. A.A. Linninger, "Design and assessment of batch pharmaceutical processes", Lecture presented at ETH Zuerich, 1995. |
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| 1994 | ||||||||||||||||||||||||||||||||||||||||||||||
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A.A Linninger, S. A. Ali, E. Stephanopoulos, C. Han, G. Stephanopoulos, "Synthesis and assessment of batch processes for pollution prevention", AIChE Symposium Series, 90 (303), pp 46-53, 1994. A.A. Linninger, G. Stephanopoulos, "Batch design-kit - An expert system model for chemists and process developers", Proc. Conference for Life-Cycles of Energetic Materials, pp 127-137, Del Mar, CA, 1994. |
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